Subject Heading

Description

Retrovirus-associated DNA sequences (v-sis) originally isolated from the simian sarcoma virus (SSV). The proto-oncogene c-sis codes for a growth factor which is the B chain of PLATELET-DERIVED GROWTH FACTOR. v-sis or overexpression of c-sis causes tumorigenesis. The human sis gene is located at 22q12.3-13.1 on the long arm of chromosome 22. [1]

Categorization Schemas

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Concepts

PSIID [2]

10820926
NLM Medical Subject Headings (MeSH) [1]

M0328536 ( Genes, sis )

Terms

Genes, sis

sis Genes

PSIID [2]

12397090
NLM Medical Subject Headings (MeSH) [1]

M0328704 ( v-sis Genes )

Terms

sis Oncogene

v-sis Genes

v-sis Oncogenes

PSIID [2]

12411935
NLM Medical Subject Headings (MeSH) [1]

M0331559 ( c-sis Genes )

Terms

Genes, PDGFB

c-sis Genes

c-sis Proto-Oncogenes

Periodicals

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Publications

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physiology

radiation effects


Last Update : 2018-12-18 | Date Created : 2014-04-17